Antibody-Drug Conjugates: The 21st Century Magic Bullets for by Jeffrey Wang,Wei-Chiang Shen,Jennica L. Zaro PDF

By Jeffrey Wang,Wei-Chiang Shen,Jennica L. Zaro

This authoritative quantity offers a holistic photo of antibody-drug conjugates (ADCs). Fourteen accomplished chapters are divided into six sections together with an creation to ADCs, the ADC build, improvement matters, panorama, IP and pharmacoeconomics, case experiences, and the way forward for the sector. The booklet examines every thing from the choice of the antibody, the drug, and the linker to a dialogue of developmental concerns resembling formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory demanding situations. It additionally explores pharmacoecomonics and highbrow homes, together with lately issued patents and the associated fee research of drug treatment. Case reviews are provided for the 3 ADCs that experience obtained FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), in addition to an ADC in late-stage scientific trials, glembatumumab vedotin (CDX-011). eventually, the amount offers a point of view by means of the editors at the destiny instructions of ADC improvement and scientific functions. Antibody-Drug Conjugates is a pragmatic and systematic source for scientists, professors, and scholars drawn to increasing their wisdom of state-of-the-art study during this intriguing field.

Show description

Read Online or Download Antibody-Drug Conjugates: The 21st Century Magic Bullets for Cancer (AAPS Advances in the Pharmaceutical Sciences Series) PDF

Best pharmacology books

International Handbook of Foodborne Pathogens (Food Science - download pdf or read online

This reference describes the administration, keep watch over, and prevention of microbial foodborne sickness. It analyzes changes within the epidemiology of foodborne affliction from elevated transnational foodstuff alternate to examinations of latest and rising zoonoses. It additionally discusses the superiority and chance of foodborne illness in constructing and industrialized international locations.

Get Getting Started as a Pharmacy Preceptor PDF

This hassle-free publication should be a convenient source for brand spanking new preceptors, these contemplating changing into preceptors, and pro preceptors in any perform environment. Written in a conversational tone and containing examples and illustrated situations, Getting all started as a Pharmacy Preceptor covers the basic info to turn into and be triumphant as a pharmacy preceptor for introductory and complex pharmacy perform reports (IPPEs and APPEs).

Read e-book online Palliative Care: Handbuch für Pflege und Begleitung (German PDF

Menschen, die Sterbende begleiten oder pflegen, benötigen professionelle Antworten für alle palliativen Arbeitsfelder – ob ambulant oder stationär. Dieses Handbuch umfasst alle Aspekte für die Pflege und Begleitung von Sterbenden und ihren Angehörigen: Schmerztherapie, Symptomkontrolle, Kommunikation mit Sterbenden, testomony, Patientenverfügung, Vorsorgevollmacht, sterbende Kinder, Selbstpflege, Adressen, Musterschreiben und Gesetzestexte.

Download PDF by Blaine Templar Smith: Remington Education: Physical Pharmacy

Remington schooling: actual Pharmacy offers a succinct evaluation of the foundations and functions of actual pharmacy.

Additional resources for Antibody-Drug Conjugates: The 21st Century Magic Bullets for Cancer (AAPS Advances in the Pharmaceutical Sciences Series)

Example text

Download PDF sample

Antibody-Drug Conjugates: The 21st Century Magic Bullets for Cancer (AAPS Advances in the Pharmaceutical Sciences Series) by Jeffrey Wang,Wei-Chiang Shen,Jennica L. Zaro


by Anthony
4.3

Rated 4.82 of 5 – based on 4 votes